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Clinical trials for Target Tissue

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    786 result(s) found for: Target Tissue. Displaying page 1 of 40.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2007-007958-54 Sponsor Protocol Number: Line_SD-MD_1 Start Date*: 2008-04-28
    Sponsor Name:Department of Clinical Pharmacology, Medical University of Vienna
    Full Title: Target site pharmacokinetics of linezolid after single and multiple doses in diabetes patients with soft tissue infection
    Medical condition: diabetic patients with soft tissue infection, necessiting antibiotic therapy
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-003107-36 Sponsor Protocol Number: AmoClav-Protokoll2.0 Start Date*: 2005-10-21
    Sponsor Name:Department of Thoracic and Hyperbaric Surgery, University Medical School Graz
    Full Title: Pharmacokinetic of Amoxicillin and Clavulanacid in pneumonic, interstitial lung tissue measured by in vivo microdialysis, in patients with pleural empyema treated by decortication.
    Medical condition: To measure the time versus concentration profile of Amoxicillin and Clavulanacid in the interstitial space of infected lung tissue as the target site of infection following intravenous administrati...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2004-002872-41 Sponsor Protocol Number: ELR100710 Start Date*: 2005-10-18
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A Study to Validate Key Therapeutic Targets and Biomarkers during Allergen Exposure in Subjects with Allergic Rhinitis
    Medical condition: Seasonal allergic rhinitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-004581-10 Sponsor Protocol Number: CL2-201086-002 Start Date*: 2018-09-04
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Efficacy and safety of 3 doses of S201086/GLPG1972 administered orally once daily in patients with knee osteoarthritis. A 52-week international, multi-regional, multi-center, randomized, double-bli...
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) HU (Completed) DK (Completed) PL (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2008-003636-38 Sponsor Protocol Number: SBG-1-13 Start Date*: 2008-09-22
    Sponsor Name:Biotec Pharmacon ASA
    Full Title: Estudio aleatorizado, doble ciego, controlado con placebo para evaluar la eficacia y seguridad de beta-1,3/1,6- glucano soluble (SBG) en úlceras crónicas del pie en pacientes con diabetes. A random...
    Medical condition: Úlceras crónicas del pie en pacientes con diabetes Chronic foot ulcers in patients with diabetes
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012664 Diabetic foot ulcer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024483-17 Sponsor Protocol Number: E7389-G000-309 Start Date*: 2011-06-30
    Sponsor Name:Eisai Ltd
    Full Title: A Randomised, Open-label, Multicenter, Phase 3 Study to Compare the Efficacy and Safety of Eribulin with Dacarbazine in Subjects with Soft Tissue Sarcoma.
    Medical condition: Soft tissue sarcoma (STS)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10041299 Soft tissue sarcomas HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed) CZ (Completed) GB (Completed) AT (Completed) DK (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-004437-15 Sponsor Protocol Number: ONC-2006-002 Start Date*: 2006-11-24
    Sponsor Name:ISTITUTO CLINICO HUMANITAS
    Full Title: FASE II PROSPECTIVE STUDY BAY-43-90006 IN ADVANCED, METASTATIC SOFT TISSUE SARCOMAS, AFTER ANTRACYCLINE-BASED THERAPY
    Medical condition: Histologically documented, progressive, advanced or metastatic sarcoma after adjuvant and/or first line antracycline-based regimen
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10041299 Soft tissue sarcomas HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-000035-89 Sponsor Protocol Number: Start Date*: 2011-02-16
    Sponsor Name:Med. Univ. Wien, Klinik für klinische Pharmakologie
    Full Title: Target site pharmacokinetics of doripenem at steady state in intubated intensive care patients
    Medical condition: We will carry out the present study to determine concentrations of doripenem in plasma, in the interstitial space fluid of the subcutaneous and muscle tissue and ELF in 20 intubated intensive care ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2020-001219-26 Sponsor Protocol Number: N20PIP Start Date*: 2021-02-11
    Sponsor Name:tichting Het Nederlands Kanker Instituut_Antoni van Leeuwenhoek
    Full Title: Prostatic Artery Injection vs Intra-Venous Injection of 18F-DCFPyL to evaluate treatment strategy in Prostate Cancer
    Medical condition: Prostate cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000377-40 Sponsor Protocol Number: MST-188-07 Start Date*: 2014-11-13
    Sponsor Name:Mast Therapeutics, Inc.
    Full Title: Evaluation of MST-188 in Acute Lower Limb Ischemia: A Phase 2 Randomized Double-Blind, Placebo-Controlled, Multi-Center Clinical Trial Evaluating the Safety and Efficacy Of MST-188 in Subjects with...
    Medical condition: Acute Lower Limb Ischemia
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004866 10066920 Leg ischemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-000875-20 Sponsor Protocol Number: C3291028 Start Date*: 2020-05-14
    Sponsor Name:Pfizer Inc.
    Full Title: A Phase 2b, Multi Center, Randomized, Double-Blind, Vehicle-Controlled, Intra-Participant Study, to Evaluate Efficacy and Safety of Two Regimens of Crisaborole Ointment 2% in Japanese Pediatric and...
    Medical condition: Atopic Dermatitis
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-001614-41 Sponsor Protocol Number: CSTI571BIT06 Start Date*: 2005-05-19
    Sponsor Name:NOVARTIS FARMA
    Full Title: OPEN-LABEL TRIAL OF GLIVEC IMATINIB MESYLATE IN PATIENTS WITH REFRACTORY DESMOPLASTIC SMALL ROUND CELL TUMORS DSRCT EXPRESSING A MOLECULAR TARGET OF GLIVEC PDGF-R AND/OR C-KIT
    Medical condition: TREATMENT OF PATIENTS WITH REFRACTORY DESMOPLASTIC SMALL ROUND CELL TUMORS DSRCT .
    Disease: Version SOC Term Classification Code Term Level
    6.1 10039491 PT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-000536-10 Sponsor Protocol Number: LL-37002 Start Date*: 2018-08-13
    Sponsor Name:Promore Pharma AB
    Full Title: A Study in Patients with Hard-to-Heal Venous Leg Ulcers to Measure Efficacy and Safety of Locally Administered LL-37; A Phase IIb, Double-blind, Randomised, Placebo-controlled, Multi-centre Trial
    Medical condition: Hard-to-Heal (HTH) venous leg ulcer
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004858 10066677 Chronic leg ulcer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: View results
    EudraCT Number: 2011-003145-17 Sponsor Protocol Number: TH-CR-406/SARC021 Start Date*: 2012-02-28
    Sponsor Name:Threshold Pharmaceuticals, Inc.
    Full Title: A Randomized Phase 3, Multicenter, Open-Label Study Comparing TH-302 in Combination with Doxorubicin vs. Doxorubicin Alone in Subjects with Locally Advanced Unresectable or Metastatic Soft Tissue S...
    Medical condition: Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10041299 Soft tissue sarcomas HLGT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DE (Completed) HU (Completed) PL (Prematurely Ended) BE (Completed) IT (Completed) AT (Prematurely Ended) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-000934-77 Sponsor Protocol Number: 4.0 Start Date*: 2018-05-11
    Sponsor Name:Medical University of Vienna
    Full Title: Target attainment of Cefazolin Continuous Infusion for Antibiotic Prophylaxis in patients undergoing CABG surgery
    Medical condition: Patients referred for CABG to the Department of Cardiac Surgery with planned isolated left mammary artery and vein/radial artery grafts preparation will be asked to participate in this trial.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003615-22 Sponsor Protocol Number: EXP-1373 Start Date*: 2019-05-28
    Sponsor Name:LEO Pharma A/S
    Full Title: Efficacy and safety of twice-daily application of delgocitinib cream 20 mg/g for 6 weeks in subjects with active discoid lupus erythematosus. A phase 2a exploratory, randomised, double-blind, vehi...
    Medical condition: Discoid lupus erythematosus
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004858 10013072 Discoid lupus erythematosus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) DK (Prematurely Ended) FR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-003462-18 Sponsor Protocol Number: AP23573-07-302 Start Date*: 2008-06-03
    Sponsor Name:Merck Sharp & Dohme Corporation, a subsidiary of Merck & Co, Inc.
    Full Title: A Pivotal Trial to Determine the Efficacy and Safety of AP23573 (Ridaforolimus) when Administered as Maintenance Therapy to Patients with Metastatic Soft-Tissue or Bone Sarcomas
    Medical condition: Patients who have benefited from cytotoxic chemotherapy. Patients will have either metastatic soft-tissue or bone sarcoma, with histological category (soft-tissue or bone) as one of the baseline s...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10041299 Soft tissue sarcomas HLGT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006008 Bone sarcoma NOS LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) CZ (Completed) BE (Completed) SE (Completed) ES (Completed) FR (Completed) NL (Prematurely Ended) GR (Completed) SK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-006153-41 Sponsor Protocol Number: J&P004/2008 Start Date*: 2009-03-30
    Sponsor Name:Medical university Graz, Department of Plastic Surgery
    Full Title: Target site pharmacokinetics of linezolid after repetitive doses in diabetic patients with bacterial foot infection
    Medical condition: The study population will consist of a representative group of adult male or female patients with documented diabetes and bacterial soft tissue infection of the foot complicated by osteomyelitis. P...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-018851-88 Sponsor Protocol Number: IPR/23 Start Date*: 2010-09-27
    Sponsor Name:MOLMED
    Full Title: NGR016: Randomized phase II study evaluating two doses of NGR-hTNF administered either as single agent or in combination with doxorubicin in patients with advanced soft-tissue sarcoma (STS).
    Medical condition: Locally advanced or metastatic STS patients untreated or previously treated with one or more prior systemic regimen.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10041299 HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-004538-32 Sponsor Protocol Number: LIMTOP-I Start Date*: 2012-04-04
    Sponsor Name:Moberg Derma
    Full Title: A double-blind, randomized, multi-centre, vehicle-controlled study of efficacy and safety of a new topical formulation with imiquimod (Limtop) applied 1,3 or 7 times weekly during 2 x 2 weeks treat...
    Medical condition: 5-20 clinically confirmed, palpable or visible (grade I or II according to modified Olsen score), nonhyperkeratotic, nonhypertrophic, AK lesions located within a contiguous (25 - 100 cm²) area on t...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10040785 - Skin and subcutaneous tissue disorders 10000614 Actinic keratosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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